KEVIS

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Maintaining a youthful appearance with thicker, fuller-looking hair, is possible as long as you know how. Kevis Rejuvenation Programs, Inc. was created to bring state-of-the-art European anti-aging products to North America and educate people on the body's aging processes and how to counter-act them.

Hair thinning or loss affects 25 million men and 20 million women in the United States and is an area of concern for most of these people. There are many products and procedures available that claim to be the answer but how does the average person know which route is the best to take. The answer to this is to learn what causes hair thinning/loss and then find the product or procedure that is designed to control or reverse the cause of the problem.

If you want to know how to have and maintain healthier, fuller-looking hair, keep reading...

Kevis Hair Rejuvenation Program

INTRODUCTION

We are pleased to present Kevis® Hair Lotion and Shampoo, the leading drug free, cruelty-free and clinically tested thinning hair treatment from Europe. Kevis is not a drug so it requires no medical supervision. Also Kevis contains no harmful chemicals, produces no side effects and is safe and effective for men and women of all ages. It is easy to use and very cost efficient. Kevis will help you prevent hair loss and your hair will be healthier than ever before.

The active ingredients in Kevis were first identified during cardiovascular research. Scientists discovered that these ingredients had a positive effect on thinning hair follicles when applied topically. It was only after years of additional studies and tests that the specialists at Kevis laboratories achieved the ideal combination of active ingredients that are unique to Kevis.

Kevis is a unique hair improvement treatment program. It goes far beyond earlier products, for unsurpassed results.

Kevis is so unique it was granted an official U.S. patent based on successful clinical testing and prior European patents. Kevis is now being introduced to the U.S.A. after an unprecedented success in the European dermatological and pharmaceutical professional circles.

Many theories exist as to why people suffer from hair loss.. These hypotheses vary in scope regarding the subject. There is, however, a major consensus in all reasonable hypotheses: deprivation, in some form, to the follicle and scalp. In general, we lean towards the conversion of testosterone into DHT, and the subsequent binding of this molecule to its receptor sites as the primary instigator of hair loss. Most modern medical research sides with this position. Furthermore, it has been also proved that there is a decrease of glycosamynoglycans in the dermal papilla during hair loss.

Europe's Finest Clinically Tested Hair Improvement Program

In Europe, KEVIS has been scientifically tested and has proven its effectiveness in households all around the world. Currently, KEVIS is successful and enjoying multimillion dollar sales as well as the appreciation that comes from enhancing overall health and attractiveness in people everywhere. We are pleased to bring the comprehensive benefits and availability of KEVIS products to the United States, where both the desire and concern for health is at its highest.

As we mature, there is a progressive deterioration of our hair follicles, with a reduction in essential nutrients in and around the follicles where hair is created and grows. KEVIS is able to replace these missing nutrients by actually penetrating both hair follicles and hair shafts, delivering its unique, patented complex formulation deep into the hair generating areas of the scalp.

Dr. Renato Venafra discovered that these complex carbohydrate molecules-acid polysaccharides- had a positive effect on hair follicles when applied topically. It was only after years of additional studies and tests that Dr. Renato Venafra achieved the ideal combination of active ingredients.

The Kevis Hair Lotion has been tested extensively at Italy's universities of Milan, Pavia and Parma, and at France's University of Marseilles.

Daily hair-loss is normal. When daily hair-loss amounts are greater than the new hair growth, you should take immediate steps to correct this condition because thinning hair will soon be a fact of life. Whatever is causing your hair problem has a direct effect upon the hair follicle.

Kevis Hair Improvement Program

The hair follicle is a sophisticated receptacle within the scalp from which hair grows, by a process described as protein and carbohydrate synthesis. As one of the most active cellular parts of your body, the follicle is extremely sensitive to internal and external changes.

A decrease in hair quantity and quality can be a result of numerous causes. Some are as simple as using the wrong shampoo, to more serious problems requiring medical attention.

Thick, strong, healthy hair really begins with good scalp hygiene. Most conventional shampoos do not adequately clean the scalp because they leave gummy resin residue behind that blocks the follicle. Some are too harsh and strip essential oils, irritating the follicle.

Kevis shampoo with H.U.C.P. is an exceptional gentle hair and scalp cleanser which replaces conventional shampoo.

Kevis Shampoo

ï Kevis forms a protective film to prevent dehydration of the scalp and hair. Plus increases skin elasticity and hydrates the scalp.

ï Kevis' amino acids help maintain the protein structure of the hair.

ï Kevis contains copolymers which upon application forms a protective sheath around the hair structure resulting in increased body, sheen and easy combing.

Kevis Hair Lotion

Within minutes after each Kevis treatment you will feel a warm, glowing sensation in the scalp. This is the effect of Kevis penetration of stimulating nutrients to restore deteriorating follicles, increasing micro- circulation and helping all hair follicles to become more vibrant and productive. Kevis helps inhibit testosterone aggression, which can weaken, rather than strengthen thinning hair.

Ten days after starting the Kevis treatment, your hair will definitely look and feel healthier. Kevis has been proven to increase the percentage of actively growing healthy hair and reduce the percentage of weak, dormant hair.

Kevis can be used as often as you like without the worry of side effects. Increased dosages and frequency, plus additional massage may improve results.

Hair after passing through the Telogen Phase, may take 2 - 4 months before it can be seen above the scalp. Different hairs are at various stages of their life cycle. Understanding this will enable you to make a commitment to improve the health of your hair and scalp, and will give you the power and patience you need to follow through.

We suggest a one year commitment to achieve maximum results

How Kevis Hair Products Work

KevisÆ penetrates the scalp, the hair follicles and the cuticle of the hair shaft to enrich and revive deteriorating hair follicles and actually thickens and smoothes even damaged hair shafts. Kevis combats thinning from the inside.

As we mature, there is a progressive reduction of the size of the hair follicles, with a reduction in acid polysaccharides in and around the follicles, where hair is created and grows. Kevis penetrating action delivers the unique formulation deep into the hair-generating areas of the scalp. Reconditioning benefits begin with the first treatment.

Kevis's exclusive formulation of HUCP and thioglycoran is rich in highly refined and purified acid polysaccharides and hyaluronic acid derived from unique European extracts and biotechnology. The penetrating action of Thurfyl Nicotinate delivers these stimulating nutrients deep into the hair follicles and hair shafts while improving microcirculation of the scalp. Vitamins Na-Pantothenate and Biotin (H) help synthesize CoEnzyme A, a molecule of hair metabolism.

In Europe Kevis has been recognized as having the ability to protect the hair follicle receptors from the DHT aggression. Kevis protects the hair growth cycle by inhibiting build up in the hair follicle. Kevis was granted a U.S. Patent on August 23, 1994.

Kevis scientists have created the ideal "human-quality" molecules, unlike other products, Kevis's nutrients are compatible and identical to those occurring naturally in the human hair, scalp and follicle.

Kevis can be used safely by all people since it is drug free and does not enter the blood stream.

PROPER CLEANSING OF THE SCALP

Dandruff, psoriasis, oily hair, wax build-up, etc., all can contribute to a condition of impeding healthy hair growth. Thick, strong, healthy hair really begins with good scalp hygiene. The trouble with most commercial shampoos is that they contain harsh cleansers which strip the hair and scalp of beneficial oils. This process may send the wrong signals to the sebaceous glands (oil producing glands of the scalp), to overproduce sebum. The end result is dry, wispy hair and an oily scalp. To solve this problem, Kevis shampoo cleans the hair and scalp without stripping it.

EFFECTS ON STYLING

Kevis penetrates the hair shaft, it restores the hair cuticles, and continued treatment results in a significantly smoother and thicker hair shaft. Hair is easier to comb, less likely to tangle or break, and the hair actually looks thicker. Style and work with the hair as usual. The hair will hold and style as well as or better than before.

Kevis can be used on hair that has been permed, colored, relaxed or straightened. OUR ONE PRECAUTION: We advise against a Kevis treatment on the same day as a perm, coloring or relaxing, since the scalp may be already sensitized and tender, and you could experience some discomfort. Importantly, Kevis causes no detrimental effects on hair that has been colored, permed or relaxed.

Kevis leaves no residue or build-up; it is completely absorbed within 20 minutes.

How to Use Kevis Hair Products

KEVIS® SHAMPOO

Kevis is concentrated, use about a third or half of usual amount (roughly the size of a dime). It will only slightly lather, as it contains no harsh detergents or soaps. Rinse well and towel dry.

KEVIS® HAIR LOTION (brown vial):

Treatment can be applied morning and/or bedtime to wet (after towel drying) or dry hair anytime, preferably after Kevis shampoo. Open vial carefully, apply contents gently over top of scalp and all areas of thinning hair. To aid circulation, press down on the scalp and massage Kevis in by moving the scalp against the skull (use scalp massager if available). Leave on for a minimum of 4 hours or till next shampoo. Style as usual.

NOTE: You may feel a warm glowing sensation in the scalp, accompanied by a slight flush. Do not be alarmed. This is normal and lasts approximately 30 minutes. The warmth and reddening you feel is the result of the Kevis hair lotion creating micro-circulation.

Immediate and Long-Term Benefits

First Response; Penetrating Warmth

Within minutes after each Kevis® treatment you will experience a warm, glowing sensation in the scalp, sometimes accompanied by a slight reddening. This is the effect of Kevis's penetration and stimulation of micro circulation, and is evidence to the users that something is happening. The warmth and reddening will fade within 20-30 minutes, but the benefits continue as the ingredients penetrate the scalp, hair shafts and hair follicles, delivering needed nutrients.

Second Response; 10-14 Days.

Roughly 10-14 days after the start of regular treatment with Kevis, you should begin to notice specific improvements. Hair will look and feel thicker (the cuticle starting serious repair). Scalp disorders should show some improvement. Some clients may report a slowing of hair loss, others may experience an increase in hair loss .... reassure them this is normal, as weak, Telogen hair is sloughed off to make way for new growth.

Third Response; After 90 Days.

It takes 90 days or more for the full effects of Kevis to begin to manifest themselves. After this period, when treatment is well in progress and if you followed the regimen of usage per the Correct Treatment Plan, certain benefits should become obvious.

Scalp disorders such as dandruff and seborrhea are generally corrected or are already reduced problems.

Hair will have achieved a thickness, fullness and sheen not possible with any conditioner, since the benefits are achieved from inside. Breakage will have been significantly reduced, including in difficult cases, such as the forehead region characteristic of "ponytail syndrome."

Look for a reduction in the rate of hair loss. Hair brushes and combs may be cleaner, pillows and bathtub drains may show less hair

U.S. Patent

United States Patent #: 5,340,579

Date of Patent: Aug. 23, 1994

Casero, deceased

______________________________

Method of treating dermatological conditions

Inventors: Casero, deceased; Riccardo (late of Como, IT), by Patrizia Magnasco Casero, executor, Francesca Margaret Casero, Elisabetta Giovanna, heirs .

Assignee: Farmaka S.r.l. (Grandate, IT).

Appl. No.: 541,119

Filed: Jun. 20, 1990

Related U.S. Application Data

Continuation-in-part of Ser No. 83,944, Aug. 4, 1987, abandoned, which is a continuation of Ser. No. 797,685, Nov. 13, 1985, abandoned.

Foreign Application Priority Data

Nov. 20, 1984 [IT] 23676 A/84

Intl. Cl.: A61K 35/00; A61K 37/00; A61K 37/02; A61K 37/10

U.S. Cl.: 424/114; 514/ 2; 514/ 8; 514/ 21; 514/336; 514/844; 514/847; 514/858; 514/859; 514/860; 514/861; 514/862; 514/863; 514/864; 514/865

Field of Search: 514/2, 8, 21, 336, 847, 844, 858-865; 424/114, 115-117, 70

References Cited [Referenced By:]

U.S. Patent Documents

3,887,703 Jun., 1975 Manoussos et al. 424/180

4,303,676 Dec., 1981 Balazs 424/359

4,504,494 Mar., 1985 Grollier et al. 514/544

Foreign Patent Documents

158706 Dec., 1981 JP

1198005 Mar., 1968 GB

1283892 Aug., 1972 GB

200232A Feb., 1979 GB

Other References

The Merck Index, 19th Ed., Merck and Co., Rahway, N.J. 1976, p. 624, entry No. 4634.

Clinical Pharmacology Research, "Assessment of the Effects of a Topical Product Containing Glycosaminoglycans in Cutaneous Hydration", Berardesca, E. et al.

Primary Examiner: Moezie; F. T.

Attorney, Agent or Firm: Browdy and Neimark

Abstract

A method is provided for treating dermatological conditions by binding and blocking 5-a-dihydrotestosterone receptors comprising applying to the skin an effective amount of composition comprising:

(a) from about 0.1% to about 2.0% by weight of mucopolysaccharides free of proteins and having a pH ranging from about 5 to 7.5 in aqueous solution, a rotary power between about to +15, and a sulfur content greater than 6%;

(b) from about 1% to about 3% by weight of an aqueous extract of human umbilical cord free from sulfur and having a DH of from about 5 to about 7, a viscosity of 30 deg. C. of from 10 to 25 centistokes, a hyaluronic acid titre of from about 500 to about 700 mg/dl, and an ash content of less than about 0.5%;

(d) pharmaceutically and cosmetically acceptable vehicles and excipients.

This method is particularly useful in treating dermatological conditions such as acne, wrinkles, lipodiystrophies, dermosclorosis, androgenic alopecia, hypertrichosis, and the like.